Department of Chemistry, York University, 4700 Keele Street,
Toronto, ON M3J 1P3
E-mail: c1000@careerchem.com Webpage:
http://www.chem.yorku.ca/NAMED http://www.careerchem.com/MainFrame.html
EDUCATION
|
Ph.D., University of Toronto, Toronto, CANADA; Organic
Chemistry |
1992 |
|
B.Sc., University of Toronto, Toronto, CANADA;
Biochemistry |
1987 |
PROFESSIONAL
EXPERIENCE
|
Founder of CareerChem, National Directory of
Departments of Chemistry in Canada website |
2000 - present |
|
Green
chemistry book author, Taylor & Francis, CRC Press |
2007 - present |
|
Consultant
for pharmaceutical industry (Merck &
Co., NJ; Row2 Technologies, NJ) |
2007 – present |
|
Course
Director and Lecturer, York University, CANADA CHEM 3070 Industrial and Applied Green Chemistry CHEM 4100 Research Project Supervisor CHEM 3021 Organic Chemistry III |
1999 - 2010 |
|
Visiting Scholar, University of Toronto, CANADA |
1997 – 1998 |
|
Junior Research Fellow, The University of Queensland,
AUSTRALIA |
1995 – 1997 |
|
NSERC Post-doctoral Fellow, University of Ottawa, CANADA |
1992 – 1994 |
PROFESSIONAL
AND SCHOLASTIC HONOURS
|
President, SigmaXi University of Toronto Chapter |
2004 - 2006 |
|
Vice-President, SigmaXi University of Toronto Chapter |
2003 |
|
Nominated and elected to full membership in Sigma-Xi (U of Toronto Chapter) |
1999 |
|
Australian Research Council (ARC) Junior Research Award, |
1996 |
|
University of Queensland Post-doctoral Fellowship |
1995 - 1997 |
|
NSERC Post-doctoral Fellow, University of Ottawa |
1993 - 1994 |
|
Ontario Graduate Scholarship, University of Toronto |
1989 - 1991 |
|
NSERC Post-graduate Fellow, University of Toronto |
1987 - 1989 |
|
University of Toronto Chemistry Club President |
1988 - 1989 |
|
Dean's List, University of Toronto |
1983 - 1987 |
|
NSERC Undergraduate Student Research Award, University of
Toronto, Tenured in the laboratory of
Prof. J. Bryan Jones |
1986 |
|
F.E. Beamish Prize in Chemistry, University of Toronto |
1985 - 1986 |
|
Mary H. Beatty Admission Scholarship, University of
Toronto |
1983 - 1986 |
|
Ontario Youth Medal |
1985 |
Invited
Addresses
2011
“Green
Chemistry’s Impact on Research in and Teaching of Organic Synthesis”, University of Toronto, Toronto, CANADA,
October 14, 2011
2010
“A Database Tool
for Process Chemists and Chemical Engineers to Gauge the Material and Synthetic
Efficiencies of Synthesis Plans to Industrially Important Targets”, University of Ontario Institute of
Technology, Oshawa, CANADA, October 13, 2010
2009
“Perspectives on Teaching and
Research in Green Chemistry”, University of Toronto, Toronto, CANADA, June 5,
2009
2008
"Green Chemistry Metrics: Application to Reaction and Synthesis Optimization", Apotex
Pharmachem, Inc., April 22, 2008, Brantford, Ontario, CANADA
2007
15th International Conference on Organic Process
Research and Development, "Getting a Grip on Quantifying How Efficient a
Synthesis Plan Is For a Given Target Product", San Diego, California, USA,
January 8 - 10, 2007
"Getting a Grip on Quantifying How Efficient a
Synthesis Plan Is For a Given Target Product", BioVerdant, Inc., San
Diego, California, USA, January 11, 2007
“Green Chemistry Principles, Metrics and Industrial
Implementation”
Three day training course given by Scientific Update LLP
(co-hosted with Dr. Peter L. Spargo)
Le Centre Sheraton, Montreal, June 19 – 21, 2007
Determining Product Ratios for Kinetic Schemes Without Rate
Laws: a new method based on directed
graphs, 90th CSC Conference and Exhibition, May 26 – 30, 2007,
Winnipeg, Manitoba, CANADA (in honour of Prof. A. Jerry Kresge)
Green Chemistry Metrics for Reaction and Synthesis
Optimization, Merck & Co., Rahway, NJ, October 16, 2007
University of Toronto, Sigma-Xi invited address, "The
"Algebra" of Organic Synthesis:
Green Chemistry and Synthesis Optimization", November 22, 2007
2006
CIC Chair’s Event:
Diversity in Chemical Careers Panel Discussion
“Pursuing an Academic Career in Chemistry”, CSC Conference
and Exhibition 2006, Halifax, Nova Scotia, CANADA, May 27 – 31, 2006
2005
Green Chemistry and Engineering Education Workshop, Chemical
Sciences Roundtable, "Green Chemistry:
Teaching and Research", National Academies, Washington, D.C., USA,
November 7 - 8, 2005 pdf
2004
University of Toronto, Sigma-Xi invited address,
"Connections in Science:
implications on idea generation and career development", January
22, 2004
87th CSC Conference and Exhibition, London,
Ontario, "New Paradigms in Teaching and Doing Research in Organic
Chemistry", May 31, 2004
2003
Concordia University, "Careers in Chemistry: Pursuing Academic Careers in Canada", 6th
Chemistry and Biochemistry Graduate Research Conference, November 15, 2003
2000
York University (York Chemical Society), "Did You
Know? A Who's Who of Chemistry",
September 22, 2000.
PROFESSIONAL
TEACHING EXPERIENCE
York
University and University of Toronto 1999
- 2009
Departments of Chemistry, Toronto, CANADA
Course
Director and Lecturer
Lectured honours undergraduate and graduate level courses in
mechanistic, synthetic organic, and industrial chemistry (CHEM 3021/3070/4023/5030 at York, CHM 1045 at U Toronto) covering topics in organic synthesis,
environmental ("green") chemistry methods, industrial process
chemistry, reaction optimization, mathematics of kinetic systems, linear free
energy relationships, proton transfer reactions, isotope effects, and reaction
intermediates; 36 one hour sessions held 3 days a week; enrollment: 10 to 50
students.
·
Launched first "green chemistry" course in the
Department of Chemistry at York University (CHEM 3070: Industrial and
Applied Green Chemistry), 2002
·
Revised course syllabuses including design of writing
assignments and problem sets, design of laboratory experiments complementing
lecture material, development of critical skills in oral presentations and
literature critiquing.
·
Implemented novel pedagogical strategies not found in
textbooks including vocabulary listing, flowcharting of concepts, in-class
problem solving, and scientist biographical sketching.
·
Upgraded and expanded collection of texts in chemistry at
Steacie Science Library (contact Leila
Fernandes, Chemistry Liaison Librarian, Steacie Science Library).
·
Developed webpage “Named
Things in Chemistry and Physics”, http://www.chem.yorku.ca/NAMED/
and http://www.careerchem.com/NAMED/Homepage.html
as a resource database for important concepts in chemistry and physics (related
to chemistry) including original scientific citations, scientific genealogies,
and biographical references
·
Completed "The
University Teaching Practicum", 1999 – 2001 (Co-ordinator: Prof.
Pat Rogers)
·
Completed "TeachTech"
Summer Workshops (Multimedia Resources in Teaching), Summer 1999
(Co-ordinators: Prof. Peggy Keall and
Rob Finlayson)
·
Launched "Charting a Career in Science in Canada"
panel discussions at the University of Toronto as part of SigmaXi U of Toronto
outreach programs for undergraduate and graduate students (2004)
PROFESSIONAL
RESEARCH EXPERIENCE
York University 2000
- 2009
Department of Chemistry, Toronto, CANADA
·
Application of reaction metrics for analysis of organic
reactions and total syntheses of organic molecules; optimization of recycling
and reagent retrieval protocols; discovery of new multi-component reactions by
structural combinatorial techniques; unified mathematical analysis of green
metrics; molecular complexity
·
Quantification and optimization of dynamic kinetic
resolution relevant to stereoselective syntheses of pharmaceuticals and
sedatives (thalidomide); advanced mathematical analysis; analytical and
numerical solution of systems of differential equations encountered in kinetics
problems in homogeneous and heterogeneous chemical systems
·
Dynamic NMR studies on novel phthalocyanines relevant to
photodynamic therapy and materials science; with Prof. Cliff Leznoff
·
Development of pedagogical exercises and computer software
for 3-D visualization of molecules relevant to the teaching of stereochemistry
to undergraduates in years 2 and 3; with Prof.
Walter Whiteley, Department of Mathematics and Statistics
University of
Toronto 1997 - 2000
Departments of Chemistry, Toronto, CANADA
Visiting
Scientist
Kinetic investigation of complex chemical systems in
solution and in heterogeneous media
·
Unified kinetic methodologies for describing complex kinetic
behaviour in matrices, polymers, zeolites, and other restricted media including
Kohlrausch-Williams-Watts, Albery-Siebrand, exponential series method (ESM),
and maximum entropy method (MEM) analyses.
The University
of Queensland 1995
- 1997
Department of
Chemistry, Brisbane, AUSTRALIA
Junior Staff Researcher: (with
Professor C. Wentrup)
Mechanistic studies of novel thermolytic and photolytic
rearrangements of cumulenes by matrix isolation FT-IR spectroscopy and variable
temperature NMR.
·
Awarded an $18,000 Australian Research Council grant for
Junior Researchers.
·
Developed methods of implementing heterogeneous phase
reaction modelling techniques involving time-dependent rate constants and
distribution analysis using commercially available software packages.
·
Discovery of novel heterocumulenes by pyrolysis and
photolysis of heterocyclic compounds and study by low temperature FT-IR matrix
isolation spectroscopy
University of
Ottawa 1993
- 1994
Department of
Chemistry, Ottawa, CANADA
NSERC Post-doctoral Fellow: (with Professor J.C. Scaiano)
Mechanistic studies of photochemical reactions by
time-resolved laser flash photolysis in solution and in zeolites.
·
Developed a GC/MS protocol for the elucidation of reaction
mechanism for photoacid generation from sulfonic acid derivatives (with Shipley
Co.)
·
Developed computational methods for treatment of kinetic
data of photochemical reactions in heterogeneous media; generalization of
calculation protocols
University of
Toronto 1987
- 1992
Department of
Chemistry, Toronto, CANADA
Graduate Student and Teaching Assistant: (with Professor A.J. Kresge - deceased)
Investigation of ketene hydration reaction mechanism in aqueous
solution by time-resolved flash photolysis and ab initio computational methodologies.
·
Built and designed $200,000 laser flash photolysis facility
at the University of Toronto shared among 3 research groups with a total of 12
personnel.
Universität
Basel 1991
Institut für
Physikalische Chemie, Basel, SWITZERLAND
Visiting Doctoral Student: (with Professor Jakob Wirz)
PROFESSIONAL
AFFILIATIONS
Canadian Society of
Chemistry (CSC, 1988 - )
American Chemical Society
(ACS, 1988 -)
Inter-American Photochemical
Society (IAPS, 1993 - )
Mathematical Association of
America (MAA, 1993 - )
Royal Canadian
Institute (RCI, 1997 - )
Sigma-Xi (1999 - )
Reviewer for Journal
of the American Chemical Society, Journal
of Organic Chemistry, Organic Letters, Journal of Physical Organic Chemistry,
Journal of Chemical Education, Journal of
Theoretical Biology
Editorial Board Member:
The Open Current Process Chemistry Journal
Executive
Board member (2001 – 2004), Sigma-Xi
University of Toronto Chapter
Member of Faculty of Pure and Applied Science Council, York
University (2002 - 2010)
SPECIAL
SKILLS
COMPUTER
PROGRAMS:
|
Operating Systems |
UNIX; MAC System 7.5; Windows 2000 |
|
Programming |
TrueBASIC |
|
Word Processing |
Word; PowerPoint |
|
Chemical Structures |
ChemWindows; ChemDraw |
|
Statistical and Symbolic |
Excel; KaleidaGraph; GraFit; SigmaPlot; Mathematica |
|
Computational |
GAUSSIAN90; MONSTERGAUSS; CAChe |
|
Internet |
Netscape Navigator; Explorer |
|
Databases |
CAS-STN, SciFinder Scholar, Beilstein |
LANGUAGES: English
(fully fluent); French (intermediate reading and writing); Italian,
German, and Portuguese (basic reading).
PUBLICATIONS
AND CONTRIBUTIONS
(A) Books and
Book Chapters
J. Andraos*, The Algebra of Organic Synthesis: Green
Metrics, Design Strategy, Route Selection, and Optimization, CRC
Press-Taylor & Francis: Boca Raton, 2012.
J. Andraos*, Designing a Green Organic Chemistry Lecture Course
in Green Organic Chemistry in Lecture and Laboratory, (A.P. Dicks, ed.),
Taylor & Francis: Boca Raton, 2012, Chapter 2, pp. 29 - 68.
J. Andraos*, Application of Green Metrics to Scalable
Industrial Synthesis Plans: An Update on Syntheses of Oseltamivir
Phosphate (Tamiflu) in Scalable Green Chemistry: Case Studies from the
Pharmaceutical Industry, (S.G. Koenig, ed.), Pan Stanford Publishing,
accepted.
J. Andraos*, Green Chemistry Metrics: Material Efficiency
and Strategic Synthesis Design in Encyclopedia of Sustainability Science and
Technology, (P.T. Anastas, J. Zimmerman, eds.), Springer-Verlag: New York,
2011.
J. Andraos*, Parameterization and Tracking of Optimization of Synthesis Strategy
Using Computer Spreadsheet Algorithms in Handbook of Green Chemistry – Green
Solvents (P.T. Anastas, C.J. Li, eds.), Wiley-VCH: Weinheim, accepted.
J. Andraos*, Atom Economy, Reaction Mass Efficiency, and E-factor
Green Metrics for Gauging Material Efficiencies of Reactions and Synthesis
Plans: Paradigms and Examples in The Oxford Handbook of Green
Chemistry, (W.M. Nelson, ed.), Oxford University Press: New York,
accepted.
J. Andraos*, Application of Green Metrics Analysis to Chemical
Reactions and Synthesis Plans, in Green Chemistry Metrics in Green Chemistry
Metrics, (Alexei Lapkin, David C. Constable, eds.), Blackwell
Scientific: Oxford, 2008. Chapter 4, pp. 69 - 199.
(B) Refereed
Publications
J. Andraos*; A.P. Dicks*, Green Chemistry
Teaching in Higher Education: A Review of Effective Practices, Chem. Educ.
Res. Pract., accepted.
J. Andraos*, A Green Metrics Assessment of Phosgene and
Phosgene-free Syntheses of Industrially Important Commodity Chemicals, Pure Applied
Chem. doi:10.1351/PAC-CON-11-06-12. (invited paper)
S.M. Mercer; J. Andraos, P.G. Jessop*;, Choosing the
Greenest Synthesis: a multivariate metric green chemistry exercise, J. Chem.
Educ. 2012, 89,
215-220.
L. Werner; A. Machara; B. Sullivan; I. Carrera; M.
Moser; T. Hudlicky*, J. Andraos*, Several Generations of Chemoenzymatic Synthesis of Oseltamivir (Tamiflu):
Evolution of Strategy, Quest for a Process-Quality Synthesis, and Evaluation of Efficiency, J. Org. Chem., 2011, 76, 10050-10067.
J. Andraos*, A Database Tool for Process Chemists and
Chemical Engineers to Gauge the Material and Synthetic Efficiencies of
Synthesis Plans to Industrially Important Targets, Pure Applied Chem. 2011,
83, 1361-1378. (invited paper)
J. Andraos*,
Global Green Chemistry Metrics Analysis Algorithm and Spreadsheets: Evaluation of the Material Efficiency
Performances of Synthesis Plans for Oseltamivir Phosphate (Tamiflu) as a Test
Case, Org. Process Res. Develop. 2009, 13, 161 – 185.
J. Andraos*,
Kinetic Plasticity and the Determination of Product Ratios for Kinetic Schemes
Leading to Multiple Products Without Rate Laws: new methods based on directed graphs, Can. J. Chem., 2008, 86,
342-357.
J. Andraos*,
Application of Green Metrics Analysis to Chemical Reactions and Synthesis
Plans, in Green Chemistry Metrics in Green
Chemistry Metrics, (Alexei Lapkin, David C. Constable, eds.), Blackwell
Scientific: Oxford, 2008, Chapter 4.
J. Andraos*,
The Contributions of Solomon F. Acree (1875 - 1957) and the Centennial
Anniversary of the Discovery of the Acree-Curtin-Hammett Principle", The Chemical Educator 2008, 13, 170-178.
J. Andraos*,
Gauging Material Efficiency, Canadian
Chemical News 2007, 59(4),
14 - 17.
J. Andraos*
and M. Sayed, On the Use of Green Metrics in the Undergraduate Organic
Chemistry Lecture and Practicum to Assess the Material Efficiencies of Organic
Reactions, J. Chem. Educ. 2007, 84, 1004 - 1011.
J. Andraos*,
On Using Tree Analysis to Quantify the Material, Input Energy, and Cost
Efficiencies of Simple and Complex Synthesis Plans and Networks: toward a
blueprint for quantitative total synthesis and green chemistry, Org. Process Research & Development 2006, 10, 212 - 240. pdf
J. Andraos*,
Reaction Intermediates in Organic Chemistry:
The “Big Picture”, Can. J. Chem. 2005, 83, 1415 – 1431 pdf S1-S4,
S5, S6
J. Andraos*,
Scientific Genealogies of Physical Organic and Mechanistic Chemists, Can. J. Chem. 2005, 83, 1400 – 1414 pdf S1
J. Andraos*,
Unification of Reaction Metrics for Green Chemistry II: Evaluation of Named Organic Reactions and
Application to Reaction Discovery, Org.
Process Research & Development. 2005,
9, 404 – 431 pdf
J. Andraos*,
Unification of Reaction Metrics for Green Chemistry: Applications to Reaction Analysis, Org. Process Research & Development 2005, 9, 149 – 163
S. Ebner, B. Wallfisch, J.
Andraos; I. Aitbaev, M. Kiselewsky, P.V. Bernhardt, G. Kollenz, C. Wentrup,
N-aminopyrroledione-hydrazoketene-pyrazolium oxide-pyrazolone rearrangements
and pyrazolone tautomerism, Org. Biomol.
Chem. 2003, 1, 2550 –
2555 pdf
J. Andraos*,
The Quantification and Optimization of Dynamic Kinetic Resolution, J. Phys. Chem. A 2003,
107, 2374 – 2387 pdf
N. Bhardwaj, J.
Andraos, C.C. Leznoff, The Syntheses and NMR Studies of Hexadeca- and
Octaneopentoxyphthalocyanines, Can. J.
Chem. 2002, 80, 141 – 147 pdf
N.C. deLucas, J.C. Netto-Ferreira, J. Andraos, J.C. Scaiano, Nucleophilicity toward Ketenes: Rate Constants for Addition of Amines to
Aryl Ketenes in Acetonitrile Solution, J.
Org. Chem. 2001, 66, 5016
– 5021 pdf
J. Andraos
and A.J. Kresge, Correlation of Rates of Uncatalyzed and Hydroxide-Ion
Catalyzed Ketene Hydration. A
Mechanistic Application and Solvent Isotope Effects on the Uncatalyzed
Reaction, Can. J. Chem. 2000, 78, 585 pdf
J. Andraos*,
Bimolecular Kinetics at Low Temperatures Using FT-IR Matrix Isolation
Spectroscopy: Some Caveats. Thermokinetic Parameters for the Reaction of
Fulvenones with Pyridine in Pyridine Matrices, J. Phys. Chem. A. 2000, 104,
1532 – 1543 pdf
X. Ye, J. Andraos,
H. Bibas, M.W. Wong, and C. Wentrup, Mesoions and ketene valence isomers. Pyrrolo [1,2-a]pyridiniumolates and
(2-pyridyl)carbonylketenes, J. Chem. Soc.
Perkin I 2000, 401 – 406 pdf
J. Andraos*,
E. Lathioor, and W. Leigh, Simultaneous pH-Rate Profiles Applied to the Two
Step Consecutive Sequence A ->B ->C:
A Theoretical Analysis and Experimental Investigation, J. Chem. Soc. Perkin 2 Trans., 2000, 365 – 374 pdf
J. Andraos*, A
Streamlined Approach to Solving Simple and Complex Kinetic Systems
Analytically, J. Chem. Educ. 1999, 76, 1578 – 1583 pdf
J.
Andraos*, The Problem of
Distinguishability of Rate Constants in the Two Step Consecutive Sequence A
->B ->C, Can. J. Chem. 1999, 77, 565 – 576 pdf
J.
Andraos, Y. Chiang, S.J. Eustace, A.J. Kresge, S.W. Paine, V.V.
Popik, and K. Sung, Solvent Isotope Effect on the Hydroxide-Ion Catayzed
Hydration of Ketenes in Aqueous Solution, Can.
J. Chem. 1999, 77, 459 –
462 pdf
J. Andraos*,
How Mathematics Figures in Chemistry:
Some Examples, J. Chem. Educ. 1999, 76, 258 – 267 pdf
J. Andraos,
G.G. Barclay, D.R. Medeiros, M.V. Baldovi, J.C. Scaiano, and R. Sinta, Model
Studies on the Photochemistry of Phenolic Sulfonate Photoacid Generators, Chem. Mater. 1998, 10, 1694 – 1699 pdf
J. Finnerty, J.
Andraos, Y. Yamamoto, M.W. Wong, and C. Wentrup, A Facile 1,3-Shift of
Chlorine in a Chlorocarbonylketene, J.
Am. Chem. Soc. 1998, 120,
1701 – 1704 pdf
J. Andraos,
Y. Chiang, A.J. Kresge, and V.V. Popik, Flash Photolysis of 10-Diazo-9(10H)-phenanthrenone in Aqueous
Solution. Hydration of
Fluorenylideneketene and the Fluorene-9-carboxylic Acid Keto-Enol System, J. Am. Chem. Soc. 1997, 119, 8417 – 8424 pdf
N.C. deLucas, J.C. Netto-Ferreira, J. Andraos, J. Lusztyk, B.D. Wagner, and J.C. Scaiano, Reactivity
of Fluorenylideneketene Towards Amines:
A Laser Photolysis Study with Ultraviolet and Infrared Detection, Tetrahedron Lett. 1997, 38, 5147 – 5150 pdf
G.G.H. Qiao, J.
Andraos, and C. Wentrup, Reactivity of Ketenes in Matrices: Direct Observation of Ketene-Pyridine
Ylides, J. Am. Chem. Soc. 1996, 118, 5634 – 5638 pdf
J. Andraos*,
On the Propagation of Statistical Errors for a Function of Several Variables, J. Chem. Educ. 1996, 73, 150 – 154 pdf
J. Andraos,
A.J. Kresge, and N.P. Schepp, The Hydration of Mesitylketene in Aqueous Solution: Detection of Acid Catalysis for an Aromatic
Ketene, Can. J. Chem. 1995, 73, 539 – 543 pdf
J.C. Scaiano, N.C. deLucas, J. Andraos, and H. Garcia, Determination of the Distance for
Triplet Energy Transfer in the Faujasite NaY, Chem. Phys. Lett. 1995, 233,
5 – 8 pdf
N.C. deLucas, J.
Andraos, J.C. Netto-Ferreira, and J.C. Scaiano, Laser Flash Photolysis
Study of the Reactivity of alpha-Ketenylbenzocyclobutenone with Water and
Alcohols, Tetrahedron Lett. 1995, 36, 677 – 680 pdf
J. Andraos,
Y. Chiang, A.S. Grant, H.X. Guo, and A.J. Kresge, The pKa of an
Acetylenic Amine, N-(pentafluorophenyl)-2-phenylethynamine, Ionizing as an Acid
in Aqueous Solution, J. Am. Chem. Soc.
1994, 116, 7411 – 7412 pdf
J. Andraos,
A.J. Kresge, and V.V. Popik, Kinetics and Mechanism of the Isomerization of 1H-Indene-1-carboxylic Acid to 1H-Indene-3-carboxylic Acid in Aqueous
Solution and Determination of their Keto-Enol Equilibrium Constants for the
Keto and Enol Forms. Implication on the
Photolysis of Diazonaphthoquinones, J.
Am. Chem. Soc. 1994, 116,
961 – 967 pdf
J. Andraos,
Y. Chiang, A.J. Kresge, I.G. Pojarlieff, N.P. Schepp, and J. Wirz, The
alpha-Cyano-alpha-phenylacetic Acid Keto-Enol
System. Flash Photolytic Generation of
the Enol in Aqueous Solution and Determination of the Keto-Enol Equilibrium
Constants and Acid Dissociation Constants Interrelating all Keto and Enol Forms
in that Medium, J. Am. Chem. Soc. 1994, 116, 73 – 81 pdf
J. Andraos,
Y. Chiang, C.H. Huang, A.J. Kresge, and J.C. Scaiano, Flash Photolytic
Generation and Study of Ketene and Carboxylic Acid Enol Intermediates Formed by
the Photolysis of Diazonaphthoquinones in Aqueous Solution, J. Am. Chem. Soc. 1993, 115, 10605 – 10610 pdf
A.D. Allen, J.
Andraos, A.J. Kresge, M.A. McAllister, and T.T. Tidwell, Direct Observation
and Reactivity of Transient Ketenes Generated by Flash Photolysis, J. Am. Chem. Soc. 1992, 114, 1878 – 1879 pdf
J. Andraos,
A.J. Kresge, and P.A. Obraztsov, Solvent and Secondary Substrate Isotope
Effects on the Acid-Catalyzed Ketonization of Acetophenone Enol in Aqueous
Solution, J. Phys. Org. Chem. 1992, 5, 322 – 326 pdf
J. Andraos
and A.J. Kresge, The Mechanism of the Reaction of Diphenylketene with Bases in
Aqueous Solution: Nucleophilic Attack
Versus General Base Catalysis of Ketene Hydration, J. Am. Chem. Soc. 1992, 114,
5643 – 5646 pdf
J. Andraos
and A.J. Kresge, Flash Photolytic Generation and Study of Ketenes: Acid-Catalyzed Hydration in Aqueous
Solution, J. Photochem. Photobiol. A:
Chem. 1991, 57, 165 – 173 pdf
J. Andraos*
and A.J. Kresge, Protonation and Hydration of Hydroxyketene, J. Mol. Struct. (THEOCHEM) 1991, 233, 165 – 184 pdf
J. Andraos*,
A.J. Kresge, M.R. Peterson, and I.G. Czismadia, Carboxylic Acid Enols from the
Hydration of Ketenes: A Theoretical
Investigation, J. Mol. Struct. (THEOCHEM)
1991, 232, 155 – 177 pdf
Non-referred
Publications
J.
Andraos, Speaking Up, Chem.
Eng. News 1997, 75(28),
85.
J.
Andraos, Filling the Gap, Canadian
Chem. News 2002, 54(2),
26
J.
Andraos, Nobel Breeding Ground, Chem.
Eng. News 2002, 80(40),
4.
J. Andraos, Named Things
in Chemistry and Physics, http://www.chem.yorku.ca/NAMED
(launched 2000) and http://www.careerchem.com/NAMED/Homepage.html
(launched 2003)
J. Andraos, 2001
Directory of Departments of Chemistry and Chemical Engineering in Canada, http://careerchem.com (launched 2001)
J. Andraos,
Choosing Advisors for Careers in Academia and Industry, http://www.nextwave.org
(C) Conference
Presentations (oral, unless otherwise indicated)
J. Andraos, “Combinatorial Connectivity Analysis for the
Discovery of New Multi-Component Reactions and Evaluation of their Likelihood
to be “Green” Reactions”, presented at the Sustainability Chemistry Summit
2011: From Lab to Market, September
16-18, 2011, Kingston, Ontario, CANADA
J. Andraos, "A Database Tool for Process Chemists and
Chemical Engineers to Gauge the Material and Synthetic Efficiencies of
Synthesis Plans to Industrially Important Targets", presented at the 3rd
International IUPAC Conference on Green Chemistry, August 15 - 18, 2010,
Ottawa, Ontario, CANADA
J. Andraos, "Challenges in Launching a University Level
Green Chemistry Course for Students and Professional Chemists", presented
at the 3rd International IUPAC Conference on Green Chemistry, August 15 - 18, 2010,
Ottawa, Ontario, CANADA
J. Andraos, "Challenges in Launching a University Level
Green Chemistry Course for Students and Professional Chemists", presented
at the 93rd CSC Conference and Exhibition, May 29 - June 2, 2010,
Toronto, Ontario, CANADA
J. Andraos, "Conceptual Myths Perpetrated in Organic
Chemistry Courses and Textbooks", presented at the 93rd CSC Conference and
Exhibition, May 29 - June 2, 2010, Toronto, Ontario, CANADA
J. Andraos, "Kinetic Plasticity and
Product Ratios Without Rate Laws: new
methods based on directed graphs", presented at the 35rd
Ontario-Quebec Physical Organic Chemistry Mini-Symposium in Memoriam of Prof.
Keith Yates, November 9 - 11, 2007,
University of Waterloo, Waterloo, CANADA.
J. Andraos, “Linking Synthetic Elegance,
Material Efficiency, and Green Chemistry Principles for Synthesis Design and Analysis”,
90th CSC Conference and Exhibition, May 26 – 30, 2007, Winnipeg, Manitoba, CANADA
J. Andraos, "Getting a Grip on
Quantifying How Efficient a Synthesis Plan is for a Given Target",
presented at the International Symposium on Green Chemical Processes for
Pharmaceuticals and Fine Chemicals, October 20 - 22, 2006, McGill University, Montreal, CANADA
J. Andraos and M. Sayed, "On the Use of Green Metrics in the
Undergraduate Organic Chemistry Practicum to Assess Material Efficiencies of
Organic Reactions", presented at the 89th CSC Conference and
Exhibition, May 27 - 31, 2006,
Halifax, Nova Scotia, CANADA
J. Andraos, "On Using Tree Analysis to
Quantify the Material, Input Energy, and Raw Material Cost Throughput
Efficiencies of Simple and Complex Synthesis Plans and Networks",
presented at the 89th CSC Conference and Exhibition, May 27 - 31, 2006, Halifax, Nova Scotia, CANADA
(poster)
J. Andraos, "Careers in
Chemistry: Pursuing Academic Positions
in Canada", a workshop presented at the 89th CSC Conference and
Exhibition, May 27 - 31, 2006,
Halifax, Nova Scotia, CANADA
J. Andraos, "Recent Advances in the
Determination of Kinetic Parameters in Heterogeneous Media: what we have been doing wrong!",
presented at the 33rd Ontario-Quebec Physical Organic Chemistry
Mini-Symposium, November 11 - 13, 2005,
McMaster University, Hamilton, CANADA.
J. Andraos, "Careers in
Chemistry: Pursuing Academic Positions
in Canada", a workshop presented at the 87th CSC Conference and
Exhibition, May 29 - June 1, 2004,
London, Ontario, CANADA
J. Andraos, "Named Things in
Chemistry: A New On-line Database for
Research and Teaching", presented at the 87th CSC Conference
and Exhibition, May 29 - June 1, 2004,
London, Ontario, CANADA
J. Andraos, "Unification of Reaction
Metrics: applications to reaction
analysis and reaction discovery", presented at the Canada-US Joint
Workshop on Innovative Chemistry in Clean Media, May 20 - 21, 2004, McGill University, Montreal,
Quebec, CANADA (poster)
J. Andraos and Shau-Wei Tsai, "The Effect
of Optically Pure and Impure Catalysts on the Efficiency of Dynamic Kinetic
Resolution", presented at the 31st Ontario-Quebec Physical
Organic Chemistry Mini-Symposium, November 7 - 9, 2003, University of Toronto, Toronto, CANADA.
J. Andraos, "Careers in
Chemistry: Pursuing Academic Positions
in Canada", a workshop presented at the 39th IUPAC Congress and
86th CSC Conference and Exhibition, August 10 – 15, 2003, Ottawa, CANADA
J. Andraos, “Assessing Worst Case Scenarios
for Organic Reactions using Minimum Atom Economy and Maximum Environmental
Impact Factor as Metrics, presented at the 39th IUPAC Congress and
86th CSC Conference and Exhibition, August 10 – 15, 2003, Ottawa, CANADA
J. Andraos, "Careers in
Chemistry: Pursuing Academic and
Industrial Careers in Canada", a workshop presented at the 85th
CSC Conference and Exhibition, June 1 - 6, 2002,
University of British Columbia, Vancouver, CANADA
J. Andraos, "Named Things in
Chemistry: A New On-line
Database", presented at the 85th CSC Conference and Exhibition,
June 1 - 6, 2002, University of
British Columbia, Vancouver, CANADA
(poster)
J. Andraos,
"The Canadian Chemistry Genome Project", presented at the 85th
CSC Conference and Exhibition, June 1 - 6, 2002,
University of British Columbia, Vancouver, CANADA (poster)
J. Andraos, "The Quantification and
Optimization of Dynamic Kinetic Resolution", presented at the 85th
CSC Conference and Exhibition, June 1 - 6, 2002,
University of British Columbia, Vancouver, CANADA
J. Andraos, "The Effect of Temperature
on Curtin-Hammett Kinetic Schemes and Other Problems", presented at the 85th
CSC Conference and Exhibition, June 1 - 6, 2002,
University of British Columbia, Vancouver, CANADA
J. Andraos, "Recent Advances in the
Determination of Kinetic Parameters in Heterogeneous Media", presented at
the 85th CSC Conference and Exhibition, June 1 - 6, 2002, University of British Columbia,
Vancouver, CANADA (poster)
J. Andraos, "Physical Organic
Chemistry in Canada: A Genealogy of
People and Ideas", presented at the 29th Ontario-Quebec
Physical Organic Chemistry Mini-Symposium, November 2 - 4, 2001, York University, Toronto, CANADA. (poster)
J. Andraos, "The Quantification and
Optimization of Dynamic Kinetic Resolution", presented at the 29th
Ontario-Quebec Physical Organic Chemistry Mini-Symposium, November 2 - 4, 2001, York University, Toronto, CANADA.
J. Andraos and S. Paramanantham,
“Connections Between Dynamic Kinetic Resolution
and the Curtin-Hammett Principle”, presented at the 11th
Quebec-Ontario Mini-Symposium in Synthetic and Bio-Organic Chemistry, November
10 – 12, 2000, York University,
Toronto, CANADA.
J.Andraos, E.C. Lathioor, and W.J. Leigh,
“The Problem of Distinguishability of Rate Constants in the Two Step
Consecutive Sequence: A ->B ->C.
Application to Simultaneous pH-Rate Profiles”, presented at the 82nd
Canadian Society for Chemistry Conference and Exhibition, May 30 – June 2, 1999, Toronto, Ontario, CANADA.
(poster)
J. Andraos, "The Relevance and
Usefulness of Mathematics in Chemistry Education: Illustrated Examples", presented at the 15th Biennial
Conference on Chemical Education, August 9 - 13, 1998, University of Waterloo, Waterloo, Ontario, CANADA.
J. Andraos, C. Wentrup, and G.G.H. Qiao,
"Thermokinetics of Bimolecular Reactions in Low Temperature Matrices: Simple Kinetic Models and their Implication
on Arrhenius and Eyring Analyses", presented at the 81st CSC Conference
and Exhibition, May 31 - June 4, 1998,
Whistler, British Columbia, CANADA.
J. Andraos, "The Relevance and Usefulness
of Mathematics in Chemistry Education:
Illustrated Examples", presented at the 81st CSC Conference and
Exhibition, May 31 - June 4, 1998,
Whistler, British Columbia, CANADA. (poster)
G.G. Barclay, J. Andraos, R.F. Sinta, and
J.C. Scaiano, "Photoacid Generators Based on Pentafluorobenzylsulfonate
Esters", presented at the 10th International Conference on Photopolymers
and the 5th International Conference on Polyimides, October 30 - November 4, 1994, Ellenville, New York, USA.
J. Andraos, N.C. deLucas, H. Garcia,
and J.C. Scaiano, "A Simple Distribution Analysis Approach for the
Interpretation of Reaction Dynamics in Microheterogeneous Systems.
Application to Triplet Energy Transfer in NaY
Zeolites", presented at the 21st Ontario-Quebec Physical Organic
Minisymposium, November 12 - 14, 1993,
Ottawa, Ontario, CANADA. (poster)
J. Andraos, N.C. deLucas, and J.C. Scaiano,
"Generation of Ketene Ylide Intermediates in Acetonitrile Solution",
presented at the 21st Ontario-Quebec Physical Organic Minisymposium, November
12 - 14, 1993, Ottawa, Ontario,
CANADA. (poster)
J. Andraos, Y. Chiang, G.H. Xun, and A.J. Kresge,
"Generation and Hydration of
N-(pentafluorophenyl)-2-phenylethynamine", presented at the 21st
Ontario-Quebec Physical Organic Minisymposium, November 12 - 14, 1993, Ottawa, Ontario, CANADA. (poster)
J. Andraos, J.C. Netto-Ferreira, N.C.
deLucas, and J.C. Scaiano, "The Reactivity of a-Ketenylbenzocyclobutenone",
presented at the 16th International Conference on Photochemistry, August 1 - 6,
1993, University of British
Columbia, Vancouver, British Columbia, CANADA. (poster)
J. Andraos, J.C. Scaiano, A.J. Kresge, and
C.G. Huang, "The Characterization of Ketene and Ketene Hydrate
Intermediates from Photolysis of o-Diazonaphthoquinones
in Aqueous Solution", presented at the 20th Ontario-Quebec Physical
Organic Minisymposium, October 30 - November 1, 1992, McGill University, Montreal, Quebec, CANADA. (poster)
J. Andraos, Y. Chiang, A.J. Kresge, N.P. Schepp, J. Wirz,
and I.G. Pojarlieff, "Equilibria in the Phenylcyanoacetic Acid
Keto-Enol System", presented at the Toronto International Conference on
Organic Reactive Intermediates (TICORDI), July 30 - August 1, 1992, University
of Toronto Scarborough Campus, Toronto, Ontario, CANADA and at the 11th International
Conference on Physical Organic Chemistry, August 2 - 7, 1992, Ithaca College, Ithaca, New York, USA.
J. Andraos and A.J. Kresge, "Hydration
of Ketenes: General Base Catalysis or
Nucleophilic Addition?", presented at the 18th Ontario-Quebec Physical
Organic Minisymposium, November 9 - 11, 1990,
Queen's University, Kingston, Ontario, CANADA.
J. Andraos, M.R. Peterson, and A.J. Kresge,
"Carboxylic Acid Enols from the Hydration of Ketenes", presented at
the Second World Congress of Theoretical Chemists (WATOC), July 8 - 14, 1990, Toronto, Ontario, CANADA.
(poster)